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diagnosis nephrology differential algorithm hypokalemia metabolic workup aki chloride comatose hypertension indications kidney management msk orthopedics physicalexam secondary spinalcord symptoms
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... Hypokalemia Metabolic alkalosis ... #Syndrome #Pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... postchronic hypercapnia (acute ... furosemide-like lesion) • Gitelman ... Differential #Diagnosis #Causes ... #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... clinical context and signs ... #Kidney #Injury ... #causes
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... Hypochloremic metabolic alkalosis ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... in the proximal tubule ... the indicated causes ... urine #Algorithm #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
hypertension and signs ... kidney injury). ... and metabolic alkalosis ... renal bruit or signs ... Neurologic disorders
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts: - Alkalosis ... diuretic use), Gitelman's ... Hypomagnesemia, Acute ... #Hypokalemia #Causes
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... • Mutism Pathophysiology ... : • Severe injury ... • Examine for signs ... #PhysicalExam #neurology
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