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nephrology differential alkalosis defects management metabolic rheumatology algorithm causes chloride disease fanconi hypokalemia inherited kidney liddle localization nephron symptoms table
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Bartter Syndrome ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Epithelial Cells ... acid transporter Bartter ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... Gitelman Syndrome ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #Syndrome #diagnosis ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
: Differential Diagnosis ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... periventricular white matter ... azathioprine #Behcet ... #Syndrome #diagnosis ... #management #signs
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... in the proximal tubule ... #differential #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... affects the skin, neurologic ... white and gray matter ... vasculitis • Behcet
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