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nephrology diagnosis differential alkalosis causes epithelial hypokalemia inherited kidney liddle localization management metabolic nephron table tubule
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Fanconi Syndrome ... Bartter Syndrome ... #Fanconi #Bartter ... #Pathophysiology ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... acid transporter Bartter ... ascending limb Gitelman ... Epithelial #Inherited #Defects ... #Kidney #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
indicates a renal tubule ... reabsorptive defect ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
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