11 results
diagnosis nephrology differential algorithm causes alkalosis complications low potassium psychiatry symptoms workup anorexianervosa bartter bulimianervosa chloride defects fanconi hypertension indications
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Syndrome #Pathophysiology
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
: Proximal tubule ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Renal Losses: • Metabolic ... , Gitelman syndrom ... potassium #low #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... distal convoluted tubule ... Hypochloremic metabolic ... #nephrology #management ... #pathophysiology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Pressure: - Metabolic ... , Gitelman syndrome ... Hippurate - Metabolic ... differential #potassium #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Causes of Metabolic ... furosemide-like lesion) • Gitelman ... thiazide-sensitive site) Metabolic ... after fasting #Metabolic ... Diagnosis #Causes #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... in the proximal tubule ... urine #Algorithm #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... #Syndrome #Diagnosis ... #Workup #nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
hypertension and signs ... heart failure, neurologic ... and metabolic alkalosis ... renal bruit or signs ... Neurologic disorders
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... abuse may lead to metabolic ... ) • Overall: hypokalemia ... Complications #pathophysiology ... #diagnosis #signs
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