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diagnosis rheumatology differential management hematology agglutinin behcet behcets chronic classification cll cold criteria erythematosus hemolytic inflammatory iris leukemia lupus lymphocytic
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
disease: Uveitis ... or retinal vasculitis ... Abnormal pathergy test ... Most Common Clinical ... disease (e.g. uveitis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... (Clinical Dx). ... Eye involvement (uveitis ... inhibitors • Uveitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Necrotizing, pauci-immune ... respiratory tracts Immune ... lesions-interstitial keratitis, uveitis ... Presentation - Systemic Symptoms ... retinopathy Lab Tests
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... Uveitis, chorioretinitis ... • Cogan syndrome ... interstitial keratitis, uveitis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... • Diagnostic Test ... Donath-Landsteiner test
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... context of primary immune ... Clinical Features ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... Orange or Hep C Clinical ... with no early symptoms ... cells can indicate disease ... • Neutropenia, anemia
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... skin lesions, ocular ... Zoster flare, ocular ... recovery uveitis
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... chondritis • Ocular ... conjunctivitis, keratitis, uveitis ... tests for (not
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