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diagnosis differential management hematology signs disease erythematosus lupus sle agglutinin anemia arteritis bee behcet chronic classification cll cold cryofibrinogenemia gca
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... Aseptic necrosis of hip ... Demyelinating syndromes ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Cogan Syndrome ... Symptoms (Sx) in ... retinopathy Lab Tests ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... of shoulder and hip ... affects the skin, neurologic ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
conjunction with symptoms ... central nervous system ... MRI lesions and clinical ... consistent with MS ... #neurology #noninflammatory
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... salivary ducts Clinical ... Vasculitis: • ... phenomenon (16%) MSK ... #Rheumatology #
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... , neurologic, and ... Diagnosis = clinical ... the “Chewing gum test ... them, but urgent rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... Mycoplasma, EBV, HIV ... • Diagnostic Test
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... processes: • Systemic ... pulmonary emboli, and ocular ... Antiphospholipid syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Non-autoimmune rheumatologic ... Clinical Features ... Induced Lupus: • Symptoms
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