6 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
ml/min per 1.73 m2 ... evidence-based pharmacologic ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin ... #metformin #ACEi
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
ATP-sensitive potassium ... cells, triggering insulin ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... agent • Does not cause ... #Pharmacology # ... Summary #DM2 #diabetes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Medications: K+, ACEi ... (DM, DKA, octreotide ... VBG (acidosis), CK ... only if no clear cause ... Management #Treatment #potassium