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dm2 endocrinology metformin dosing kdigo acei algorithm arb based estimation hypoglycemics impairment inhibitors initiation management medications renal sglt2 sulfonylureas table
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents #Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... #Pharmacology # ... #Table #GFR #Hypoglycemics
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... , & an eGFR ≥ 30 ... or Type 2 diabetes ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... Weight #Based #pharmacology ... endocrinology #diabetes
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... not initiate if eGFR ... not continue if eGFR ... diabetes #endocrinology
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... cells, triggering insulin ... contraindicated in CKD ... diabetes #endocrinology
Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... #Metformin #CKD ... #pharmacology #
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Summary Mechanisms ... Contraindications: eGFR ... • Euglycemic diabetic ... diabetes #endocrinology
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