11 results
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
: Weight-Based Dosing ... (stage IV or V CKD ... #Weight #Based ... #pharmacology #endocrinology ... #diabetes #DM2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table Insulin ... Improved outcomes in CKD ... comparison #management #endocrinology ... #dm2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... appropriately • Weight-based ... #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... patients with T2D, CKD ... and CKD should ... layered evidence-based ... #Diabetes #CKD #
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... -> Stimulates Insulin ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
for Type 1 Diabetes ... calculations used in dosing ... with type 1 diabetes ... #DM1 #Pharmacology ... #Endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... medications for insulin ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... Hyperkalemia: • CKD ... Poorly controlled DM ... (Uncontrolled diabetes ... paralysis - Insulin
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
oral suspension DOSING ... 25.2 g if needed, based ... patients with CKD ... , HF, or diabetes ... #Hyperkalemia #Pharmacology