5 results
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... #CKD #pharmacology ... #algorithm #diabetes ... #titration
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... mitigated by slow titration ... #Summary #DM2 #diabetes ... #endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
to it's triple mechanism ... Additionally, titrating ... 2000 mg/day) and using ... #Metformin #Pharmacology ... #Mechanism #Diabetes
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... This mechanism helps ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... the same exact mechanism ... has a similar titration ... #Pharmacology # ... Endocrinology