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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... Weakness - Dark urine ... hour with goal urine ... hyperkalemia or ATN
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Urine Specific Gravity ... Gravity = Density of urine ... resistance to ADH) • ATN ... Dehydration • SIADH (syndrome ... EricsMedicalLectures/ #Urine
Urinary Casts in the setting of renal disease
#Clinical #Nephro #Urine #Microscopy #Casts #Comparison #Chart #ATN #AIN
renal disease #Clinical ... #Nephro #Urine ... Comparison #Chart #ATN
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
• Drummond's syndrome ... (blue diaper syndrome ... * Green Urine: ... Bag Syndrome - ... Myoglobinuria, Nutcracker syndrome
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Syndrome Chronic ... E.coli*) + alkaline urine ... #Bag #Syndrome ... pathophysiology #clinical
Muddy Brown Casts in ATN
#Clinical #Path #Nephro #Urine #Microscopy #MuddyBrownCasts #ATN
Brown Casts in ATN ... #Clinical #Path ... #Nephro #Urine ... MuddyBrownCasts #ATN
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Pathways of Purple Urine ... Bag Syndrome: Adopted ... published in Purple Urine ... Bag Syndrome: A ... #Bag #Syndrome
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... Nephritic #Nephrotic #Syndromes
Fractional Excretion of Sodium - FENa
Fractional Excretion of Sodium (FENa) = (Urine Na+ x Serum Cr)
Sodium (FENa) = (Urine ... / (Serum Na+ x Urine ... > 2% suggests ATN