7 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
: • Immune Complex ... Ig A (HSP) - ... : • Temporal arteritis ... Disease • Cogan syndrome ... #rheumatology #
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... 85%) - Colicky abdominal ... nephrotic/nephritic syndrome ... Arthralgia's (common), arthritis ... #IgA #Vasculitis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... causing endothelial injury ... - Purpura - Skin ... • IgA vasculitis ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... Schonlein Purpura (IgA ... - GI tract: abdominal ... Supply gut -> abdominal ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
of shoulder and hip ... pauci-immune GN Immune Complex ... Schonlein Purpura (IgA ... gut involvement, abdominal ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... response to local skin ... injury) • Neurologic ... • Nonsurgical abdominal ... signs #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Aseptic necrosis of hip ... (rare), Arthritis ... Demyelinating syndromes