7 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... disease to acute liver ... upper limit of normal ... Anti-LKM & Anti-ALC ... #Diagnosis #Management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : Autoimmune hepatitis ... function may be abnormal ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... • Alcoholic hepatitis
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
and Management ... - Activation: Liver ... (phenytoin) • NORMAL ... granuloma) - Autoimmune ... #differential #
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... diseases and hepatitis ... : Pneumonia • Autoimmune ... and M panel Management ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... vasculitis: 10%-16% Liver ... hepatitis, primary ... phenomenon (16%) MSK ... #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... chain assay • An abnormal ... Gap #ProteinGap #differential ... #diagnosis #hematology