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hematology differential amyloid bleeding bruising common cvid gap globulin hemostasis hypogammaglobulinemia immunodeficiency immunology protein proteingap rheumatology sarcoidosis signs sjogrens symptoms
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... Testing: • EKG • Echocardiogram ... Doppler imaging: Normal-size ... imaging of liver
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... von Willebrand syndrome ... Vasculitis • Amyloidosis ... #Differential #Diagnosis ... #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... anterior/posterior MSK ... heart (2-5%), liver ... (pain/abnormal ... #Management #Signs
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... PE, Pulmonary amyloidosis ... vasculitis: 10%-16% Liver ... phenomenon (16%) MSK ... #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... (light chain) amyloidosis ... Sarcoidosis) • Liver ... chain assay • An abnormal ... #differential #diagnosis
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