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differential management algorithm complications alkaline alp biliary caudaequina cecs cholangitis chronicexertional cirrhosis compartmentsyndrome enzymes erythematosus fatty heat heatstroke hyophosphatasia illness
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Pregnancy #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... /signs should be ... #LFTs #Abnormal ... #Algorithm #Hepatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... #workup #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver ... Most cases diagnosed ... mineralization Symptoms ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
anterior/posterior MSK ... heart (2-5%), liver ... (pain/abnormal ... LFT): 12-20%, spleen ... #Management #Signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
- Differential Diagnosis ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... #causes #stroke
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... > 20 mmHg • Normal ... CompartmentSyndrome #CECS #pathophysiology ... #diagnosis #signs ... #symptoms #msk
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