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The Pathophysiology of Fat Absorption and Causes of Malabsorption (steatorrhoea) #Fat #Malabsorption #Pathophysiology #Differential #Steatorrhea #Diarrhea #Diagnosis
Pathophysiology of Fat Absorption ... and Causes of Malabsorption
Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... increased bone Ca2+ resorption ... increased GI Ca2+ absorption ... Hypercalcemia #Causes
Causes of Hypermagnesemia Increased magnesium load - Magnesium-containing laxatives, antacids, or enemas - Treatment of pre-edampsia/eclampsia (mothers
Causes of Hypermagnesemia ... renal magnesium absorption ... Hypermagnesemia #Causes
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
Causes of Hyperferritinemia ... increased GI absorption ... Most Common Causes ... 1% Most Common Causes ... is an uncommon cause
Folate Deficiency - Causes of Decreased Folic Acid ↓ Intake: Diet, Age, Alcohol ↑ Demand: Pregnancy, Infancy, Hemolysis,
Folate Deficiency - Causes ... Severe dermatitis ↓ Absorption
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Steroids • Reduced absorption ... differential #diagnosis #causes
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Vitamin C • ↓ Absorption ... Iron #Deficiency #Causes
Hypophosphatemia - Differential Diagnosis Algorithm • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use • Redistribution/
Decreased intake/absorption ... Diagnosis #Algorithm #causes
5 D's Mnemonic for Causes of Iron Deficiency Anemia (IDA) Diet - lacking iron, vitamin C, too
D's Mnemonic for Causes ... blocking iron absorption ... Decreased Absorption ... Deficiency #Anemia #Causes
Causes of Hypocalcemia - Differential Diagnosis Decreased calcium absorption • Vitamin D deficiency -
Causes of Hypocalcemia ... Decreased calcium absorption ... Decreased intestinal absorption ... resistance to bone resorption ... Differential #Diagnosis #Causes
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