Causes of Hypercalcemia Hypercalcemia due to increased bone Ca2+ resorption: • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure, Addison's disease, Hyperthyroidism, Immobilization Hypercalcemia due to decreased urinary Ca2+ excretion: • Familial hypercalcemic hypocalciuria, Thiazides Hypercalcemia due to increased GI Ca2+ absorption: • Granulomatous diseases (sarcoidosis, tuberculosis, coccidioidomycosis, histoplasmosis) • Milk (calcium)-alkali syndrome • Vitamin D intoxication #Hypercalcemia #Causes #differential #diagnosis #calcium #high #endocrinology
