263 results
Cutis Verticis Gyrata: Idiopathic development of excess folds and furrows within the skin of the head.
Associated
furrows within the skin ... mental retardation, acromegaly ... Verticis #Gyrata #Photo
Dermatofibroma 
 - Skin-colored to brown papule or nodule 
 - Firm, indurated texture 
 -
Dermatofibroma - Skin-colored ... Male - Dimple sign ... Benign #Clinical #Photo
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... #Acromegaly #Signs
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... Images #Clinical #Photo ... #Acromegaly #Acromegalic
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... , hair growth, skin ... tags, skin thickening ... resistance pseudo-acromegaly
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... - Giantism or acromegaly ... tunnel, OSA, Incr skin
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly ... Overproduction #diagnosis #signs
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
the Mnemonic "no skin ... differential #symptoms #signs ... #dermatology #skin
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
• Delayed-type skin ... diagnosis #clinical #photo ... #signs #symptoms
Signs of Graves disease: 
• Goiter 
• Periorbital edema 
• Non-pitting edema causing hyperpigmented plaques 
•
Signs of Graves ... Graves #disease #Signs ... #Clinical #Photo