26 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... plate fusion -> acromegaly ... rare causes of acromegaly ... fraction • HTN #GrowthHormone
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... metabolic abn #GrowthHormone
#ACROMEGALY #management #algorithm #treatment
#ACROMEGALY #management
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... #Acromegaly #Signs
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... : • Classic Acromegaly ... Pathophysiology: • Acromegaly ... resistance pseudo-acromegaly ... thakre_anuj) #Acromegaly
Hirsutism - Differential Diagnosis
Defined as excessive dark, coarse, male-pattern hair growth
Hirsutism causes in premenopausal women:
 •
Cushing's Syndrome, Acromegaly ... Cushing's Syndrome, Acromegaly
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Pituitary path • Acromegaly
Acromegalic Hand: Markedly enlarged hand resulting from excess growth hormone. For reference
purposes, the comparison hand is
Acromegalic Hand ... Clinical #Photo #Acromegaly ... #Acromegalic #Hand
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Endocrinopathies - Acromegaly
Cutis Verticis Gyrata: Idiopathic development of excess folds and furrows within the skin of the head.
Associated
mental retardation, acromegaly