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Action potential in cardiomyocytes The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
Depolarization Phase ... 1: Early repolarization ... Repolarization ... Pathophysiology #Cardiac #ActionPotential ... #Repolarization
Action Potential: Depolarization and repolarization of a neuron #ActionPotential #Depolarization #Repolarization #Neuron #Neurology #Pathophysiology
Action Potential: Depolarization ... and repolarization ... of a neuron #ActionPotential ... #Depolarization ... #Repolarization
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Repolarization: ... Delays ventricular repolarization ... Repolarization: ... prolong AV node repolarization ... prolong AV node repolarization
CARDIAC MYOCYTE POTENTIALS #Pathophysiology #Cardiology #Cardiac #Myocyte #Ventricular #ActionPotentials #Channels #Phases
#Ventricular #ActionPotentials ... #Channels #Phases
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
• ↓ slope of phase ... • ↓ slope of phase ... prolong AV node repolarization ... ↑ duration of phase ... interval (delays time repolarization
Class I Antiarrhythmics and their Key Pharmacologic Properties Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer") Class IB
(phase 0) of fast-response ... • Slows depolarization ... channels involved in phase ... 3 repolarization ... • Prolongs repolarization
Major electrocardiogram findings induced by left ventricular hypertrophy (LVH) An increase in left ventricular mass augments the
alteration in repolarization ... in left atrial depolarization
Distinguishing Between Benign Early repolarization vs STEMI on EKG #Diagnosis #Cardiology #ECG #EKG #Repolarization #STEMI #Comparison #Table
Between Benign Early repolarization ... Cardiology #ECG #EKG #Repolarization
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Classes #Effect #ActionPotentials
Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization
Blockade • Slows depolarization ... Blockade • Slows depolarization ... Blockade • Slows depolarization
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