9 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
: Allergen-specific ... lgE causes mast-cell ... cell antigens, leading ... #types #allergy ... #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... causes development ... #Allergic #Reactions ... #Types #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... cellular antigen, leading ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Reactions #Table
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... , Intermediate Action ... Blockade, Fast Action ... #Pharmacology #Classification ... #Classes #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... progressive organ dysfunction ... complement • Classification ... IGG4 #Diagnosis #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... • Allergic reaction ... Causes purpura & ... Injury (TRALI): Leading ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Allergic ... Causes purpura & ... Injury (TRALI): Leading ... Transfusions #diagnosis #management ... #hematology #reactions
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... TREATMENT OPTIONS ... Histiocytosis #Diagnosis #Management