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diagnosis differential causes injury lfts management transaminitis disease nafld acute ascites chronic fattyliver nephrology saag treatment abnormal aclf albumin chemistry
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Sarcoidosis Toxic - Alcohol ... Hemochromatosis - Nonalcoholic ... fatty liver disease ... #Differential #Hepatology
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... cirrhosis, Portal ... AST:ALT > 2.5 - Alcoholic ... #Patterns #Liver ... #Injury #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • NAFLD • Alcohol ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... Causes #Acute #algorithm ... #hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... and Management Algorithm ... viremia or have cirrhosis ... #HBV #Algorithm ... Management #Treatment #Hepatology
Non-Alcoholic Fatty Liver Disease (NAFLD) - Diagnosis Algorithm Low Suspicion: ≤ 1 feature of
Non-Alcoholic Fatty ... Liver Disease ( ... NFS ≥ -1.455 #NonAlcoholic ... #Fatty #Liver # ... #hepatology
Non-Alcoholic Fatty Liver Disease (NAFLD) Progression / Prognosis Timeline • 100 patients → (over 20+ years)
Non-Alcoholic Fatty ... Liver Disease ( ... never develop cirrhosis ... Burak @kwburak #NonAlcoholic ... Prognosis #Timeline #Hepatology
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