24 results
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Metformin Treatment ... Patients With Type 2 Diabetes ... and Chronic Kidney ... 3A, 3B, or 4 Diabetes ... #CKD4 #Dosing #Pharmacology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... A1c Lowering Metformin ... /ambcarerx #Diabetes ... Tablets #Oral #DM2 #Pharmacology ... #Pills #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... • Biguanides (Metformin ... • Biguanides (Metformin ... #Medications #pharmacology ... pathophysiology #endocrinology
Metformin - oral antihyperglycemic agent for treatement of type II diabetes. 8th most prescribed drug in
Metformin - oral ... antihyperglycemic agent for treatement ... of type II diabetes ... #Pharmacology #Metformin
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... Renal Dose Adjustments ... #Renal #Dosing ... #Dose #Pharmacology ... #Diabetes
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... Kidney Disease ... eGFR < 30: Stop metformin ... deficiency Monitor kidney ... #CKD #pharmacology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Line Treatment ... for Diabetes Type ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Contraindications: • Chronic kidney ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... #pharmacology #pharmacotherapy ... #endocrinology ... #treatment
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... in the nephron (kidney ... combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... #Endocrinology