6 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... Contraindications: • Chronic kidney ... #Pharmacology # ... #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Dose (TDD) of Insulin ... elderly, chronic kidney ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
daily dose of insulin ... dose for renal ... Diabetes #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
in the nephron (kidney ... combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... double check the kidney ... #Dosing #Pharmacology ... Management #Diabetes #DM2 ... #Endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
initiation of treatment ... ml/min per 1.73 m2 ... with metformin. ... evidence-based pharmacologic ... #KDIGO #eGFR #Insulin