10 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
GPA >>> MPA > eGPA ... • MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... GPA Stanford Internal ... differential #diagnosis #algorithm
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
Differential Diagnosis MPA ... GPA → usually ... c-ANCA EGPAANCA ... (MPO) C-ANCA ( ... PR3) X-ANCA (elastase
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Guidelines for Treatment ... Polyangiitis (GPA ... Polyangiitis (MPA ... Polyangiitis (EGPA ... ACR2021 #Guidelines #algorithm
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... #Polyangiitis #MPA ... #Management #Treatment
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
): GPA (granulomatous ... polyangiitis), EGPA ... polyangiitis), MPA ... subglottic stenosis) in GPA ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
capillaritis • EGPA ... > PR3 60% • GPA ... : - Aorta and ... LFT • ESR • ANA ... (Dx: GPA, EGPA,
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
Polyangiitis (EGPA ... alone in select pts ... GC + MTX, GC + AZA ... @MithuRheum #EGPA ... Vasculitis #Management #Treatment
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
< 30 years • Aorta ... Arteritis): • Aorta ... myeloperoxidase (MPO-ANCA ... progressive) EGPA ... > PR3 60/ GPA
Orofacial Granulomatosis - Diagnosis and Management Algorithm
Idiopathic OFG: isolated swelling of the lips, BX+ non-caseating granuloma
Melkersson-Rosenthal
and Management Algorithm ... ulcer, Lymphoma, GPA ... Elimination Diet* * • 5-ASA ... Resolve w Rx of IBD Algorithm ... #treatment
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Large vessels (aorta ... • Lymphoma • GPA ... /EGPA • RA Diagnosis ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment