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differential treatment ana disease aortoenteric arteritis autoantibodies autoimmune behcet classification erythematosus fistula gca giantcell igg4 lupus mimickers myopathy myositis neuritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... : The ANA patterns ... #Antibodies #ANA ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... autoantibodies (antinuclear ... antibodies, rheumatoid ... #management #phenotypes ... workup #treatment #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
SLE-Related Auto-Antibodies ... : - ANA 95-100% ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
and Management ... duodenum Clinical Signs ... /Symptoms: • Classic ... de novo between aorta ... or within the aorta
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
and Management ... caucasian • Symptoms ... Unilateral • Signs ... 30%), Variable pattern ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign ... : antibodies directed ... #rheumatology #
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
ANCA vasculitis (AAV ... EGPA) • Auto-antibodies ... or serologies + symptoms ... • IF staining patterns ... #management #treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Glucocorticoids 5-ASA ... #management #signs ... #symptoms #rheumatology
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