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differential arthritis lupus management msk pain systemic approach disease erythematosus leukemia oncology rheumatoid testing vasculitis autoimmune behcet classification cll comparison
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... rheumatic fever • Chronic ... = RA, SLE, psoriatic ... #rheumatology # ... approach #workup
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Summary Overview: chronic ... knees, shoulders Signs ... & Symptoms: • ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... phenomenon (20%) Joints ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... arthritis • SLE ... #MSK #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... : • Acute or chronic ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... • Evolution: Chronic ... comparison #table #rheumatology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Chronic ... (to support a diagnosis ... #diagnosis #testing ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... onset of symptoms ... bone pain, fever, joint ... #Leukemia #Hematology ... #Oncology #Diagnosis
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