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management pharmacology abnormal aub cardiology cardiomyopathy chemotherapy cyp3a4 diagnosis gynecology hematology inducers inhibitors interactions obstetrics oncology perioperative peripartum pglycoprotein preop
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
available lab test ... interruption per treatment ... table ... and procedural bleeding ... with a very low bleeding
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... thereby leading ... metabolization leading ... #Interactions #Table
ED Treatment of Abnormal Uterine Bleeding Hemodynamically unstable Resuscitation • ABCs! • Fluids +
ED Treatment of ... Abnormal Uterine Bleeding ... coagulopathy Pregnancy test ... Hemodynamically stable ... Abnormal #Uterine #Bleeding
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... during Delivery • Stable ... Period • Breast-feeding ... management #cardiology #treatment
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