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Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Tests #Locations #AlkPhos ... #AST #ALT #Ddxof
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Chemistry Tests - AST ... Bilirubin Metabolism AST ... and ALT: • AST ... liver, 80% of AST ... Metabolism #ASTALT #AlkPhos
HAS-BLED Score - Hypertension: Baseline SBP > 160mmHg - Renal disease: Cr > 2.6mg/dL, on HD,
bilirubin > 2x ULN, or AST ... /ALT/alkphos > 3x
Algorithm for evaluation of elevated serum alkaline phosphatase. #Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
#phosphatase #AlkPhos
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular Level • AST ... to liver than AST ... elevated ALP • AST ... NT: ↑ • ALP > AST ... • Near normal AST
Standardized Physical Abuse Guideline <6 months of age • Social work consult • Skeletal survey • Head
survey • Head CT, AST ... , ALT, lipase ... Abdominal CT if AST ... months of age if AST ... or ALT> 80, signs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... • Severe - ALT ... • Moderate - ALT ... Pattern (ALP > ALT ... or AST): • US
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
aminotransferase (AST ... aminotransferase (ALT
Gestational Hypertension & Preeclampsia Gestational Hypertension (gHTN) • BP > 140/90 • Onset > 20 wks gestation
Thrombocytopenia • Elevated AST ... /ALT • Pulmonary ... Thrombocytopenia • Elevated AST ... /ALT • Hemolysis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury • AST ... /ALT elevation > ... Alk phos • ALT ... • R value = (ALT ... + ULN ALT) / (alkaline
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