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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... conjunctivitis • Anaphylaxis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... exposure to a likely allergen ... exposure to known allergen ... Angioedema #Anaphylaxis
Pediatric Anaphylaxis Algorithm #Anaphylaxis #Algorithm #Pediatrics #Peds #Allergy
Pediatric Anaphylaxis ... Algorithm #Anaphylaxis ... #Algorithm #Pediatrics
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Local and systemic anaphylaxis ... hay fever, food allergies ... , and drug allergies
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's
Algorithm for the management of severe or refractory anaphylaxis and related airway and vascular complications in
Algorithm for the ... or refractory anaphylaxis ... #anaphylaxis #Algorithm
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Allergens attach ... interaction of the allergen ... degranulate when the allergens
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... hours - Examples: Anaphylaxis ... Hay fever, Food allergies ... , Drug allergies
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