180 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... Complications: • Acute Asthma
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Asthma: immunopathogenesis ... Allergens attach ... interaction of the allergen ... production allergic asthma ... #Asthma #immunopathogenesis
Stepwise approach for managing asthma in youths greater than 12 years of age and adults as
approach for managing asthma ... of the National Asthma ... Allergen immunotherapy ... those with single allergies ... If asthma is well
Assessment of the Child with Chronic Asthma
Are there other allergic disorders?
 - Allergic rhinitis
 - Eczema,
Child with Chronic Asthma ... - Allergens - animal ... Stress #Chronic #Asthma
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Hay fever, Food allergies ... , Drug allergies ... , Eczema, Asthma
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism of asthma ... stimuli, including allergens ... #asthma #pathophysiology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Glucocorticoids Pugs (Allergies ... Dermatitis - Asthma
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
45yo, F; Hx of asthma ... /allergies; Cough ... Weeks) - Hx of asthma
Allergic Rhinitis
Mild to severe persistent nasal mucosal inflammation to specific allergic triggers
WHO? 
 • 1 in
Birthday • Smoke / Allergen ... Associations: • Asthma
Causes of Urticaria

Immunoglobulin E (IgE) mediated

 - Aeroallergens

 - Contact allergen

 - Food allergens

 - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen