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Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... Second Exposure to Allergen
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
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 Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's
Asthma: immunopathogenesis. Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Allergens attach ... interaction of the allergen ... degranulate when the allergens
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... hay fever, food allergies ... , and drug allergies
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... Note: Severity ... acute phase does not
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
difficult airway - Allergies ... event, follow ACC algorithm ... • HgbA1c - if not ... Chest X-ray: • Not ... revascularization does not
Inpatient History & Physical (H&P) Presentation and Note Template, SOAP Note Template Chief Complaint, History of Present
Presentation and Note ... Template, SOAP Note ... , Medications, Allergies ... #Physical #HP #Note
Inpatient History & Physical (H&P) Presentation and Note Template • Chief Complaint/Concern • History of Present
Presentation and Note ... Medications • Allergies ... #Physical #HP #Note
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