794 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
bind to harmless allergens ... Sensitization" to Allergen ... Initial exposure to allergen ... after clearance of allergen ... Allergy #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Initial exposure to allergen ... recognize antigen on allergen's ... Allergy #Immunology #pathophysiology
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
Allergens attach ... interaction of the allergen ... degranulate when the allergens ... immunopathogenesis #Pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... hay fever, food allergies ... , and drug allergies ... Classification #Pathophysiology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
stimuli, including allergens ... #asthma #pathophysiology
Causes of Urticaria

Immunoglobulin E (IgE) mediated

 - Aeroallergens

 - Contact allergen

 - Food allergens

 - Insect
Aeroallergens - Contact allergen ... - Food allergens ... mediated - Contact allergen
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... cephalosporin), Food allergies ... Immunological Target: Allergen
Assessment of the Child with Eczema
Distribution of atopic eczema - The distribution of eczema tends to
Ingestion of an allergen ... an irritant or allergen ... food or other allergens
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Hay fever, Food allergies ... , Drug allergies