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diagnosis rheumatology lupus treatment erythematosus hematology summary systemic table acrocyanosis antifungals appearances atlas coccidioides coccidioidomycosis differential druginduced hemeonc hemophagocytic heparin
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... Usual therapeutic management ... Erythematosus #Diagnosis #Management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Photosensitivity, Alopecia ... Usual therapeutic management ... #comparison #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... develops on the background ... Fever is the main clinical ... erythematosus [SLE ... Syndrome #Diagnosis #Management
TISSUE APPEARANCES ON MUSCULOSKELETAL ULTRASOUND Bone: Bone is represented as a very bright structure and appears
or ‘hypoechoic’ background ... a hyperechoic background ... You can see here ... #POCUS #Atlas #Clinical ... #Radiology #Comparison
Acrocyanosis- Here again, the cyanosis of the feet is apparent in comparison to the parent's hand
is apparent in comparison ... baby's chin in the background ... #clinical #photo
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... and permanent alopecia ... lymphoproliferative syndrome Clinical ... • Nonscarring alopecia ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... complex → plt activation ... Diagnosis: • Clinical ... Confirmatory test ↑Se ... non-heparin A/C if clinical
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... Evaluate for NMO, SLE ... Disorders: - SLE ... Myelitis #diagnosis #management
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis. Fluconazole - Low
prolongation, alopecia ... skin carcinoma, alopecia ... tolerable • Limited clinical ... #valleyfever #management ... #antifungals #comparison
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