7 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
based on GFR ... #Renal #Dosing # ... Pain #Pharmacology ... #Opiates #CKD # ... Gabapentin #Table
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Insulin Lifestyle ... Improved outcomes in CKD ... endocrinology #dm2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
• Increases insulin-mediated ... not initiate if eGFR ... not continue if eGFR ... #Summary #DM2 # ... diabetes #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Summary Mechanisms ... cells, triggering insulin ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... , & an eGFR ≥ 30 ... and CKD should ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
: Weight-Based Dosing ... (stage IV or V CKD ... #dosing #estimation ... Weight #Based #pharmacology ... #DM2