8 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... Summary Mechanisms ... #Pharmacology # ... Summary #DM2 #diabetes
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Acyclovir - Pharmacology ... Summary • Mechanism ... - selectively inhibits ... against CMV) • Dosing ... Resistance • Toxicity
NSAID Dosing in CKD
 • Carboxylic Acids: Salsalate, Choline Mg trisalicylate
 • Acetic Acids: Indomethacin, Tolmetin,
NSAID Dosing in ... trisalicylate • Acetic ... Nabumetone • COX-2 Inhibitors ... #CKD #pharmacology ... #table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
anticoagulation in North America ... clearance (calculated using ... per treatment table ... direct thrombin inhibitor ... Management #Treatment #pharmacology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Angiotensin-Converting Enzyme Inhibitors ... risk of digoxin toxicity ... increasing risk for toxicity ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... Summary Xanthine ... oxidase inhibitor ... chemotherapy Dosing ... : 100 mg/m2/dose
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
ineffective because MTX inhibits ... Leucovorin dosing ... , up to 100 mg/m2 ... evidence of marrow toxicity ... #Management #Pharmacology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
, 350 mg/m2, and ... system (RAAS) inhibitor ... every 3 months during ... cardiology #oncology #pharmacology ... #toxicity #chemotherapy