23 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... thigh bones -> chronic ... • Pernicious anemia ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
weight loss - Low ... disturbances: low ... hemolysis - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... , Elevated Cr, Low ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... Marrow Failure • Chronic ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
bowel disease, Chronic ... diarrhoea, Short bowel syndrome ... dental fixatives, Treatment ... Musculoskeletal: Low ... Haematological: Anaemia
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... test - Cogan sign ... - Peek sign ... inhibition - Chronic ... diagnosis #management #neurology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
inflammatory disease How ... with leukopenia, anemia ... tests ↑ AST ↑ ALT ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
iron deficiency anemia ... disorders - Chronic ... • Mitchell et al ... Acute Coronary Syndrome ... #causes #cardiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology