1265 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... Splenomegaly 5) Symptoms ... of anemia or thrombocytopenia ... Constitutional symptoms ... marrow failure with anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(Cold-induced symptoms ... of anemia include ... • hemolytic anemia ... IgM) • Blood smear ... disease #hemolytic #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear ... pylori test (GI symptoms ... changes), high MCV anemia ... dysplasia on the smear
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... rapid onset of symptoms ... chronic onset of symptoms ... - infiltrates (anemia ... • Peripheral smear
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... blood cell count (anemia ... Peripheral Smear ... • Aplastic Anemia ... Peripheral blood smear
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... • Peripheral smear ... • Neutropenia, anemia
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Megaloblastic Anemia vs Normal Peripheral Smear

#Megaloblastic #Anemia #Peripheral #Smear #Comparison #Clinical #Hypersegmented #Neutrophil
Megaloblastic Anemia ... Normal Peripheral Smear ... Megaloblastic #Anemia ... #Peripheral #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Microangiopathic hemolytic anemia ... Autoimmune hemolytic anemia ... Peripheral #Blood #Smear
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... BloodSmear #Blood #Smear