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Metabolic and Respiratory Acidosis and Alkalosis - Diagnostic Algorithm

Anion gap - MUDPILES:
- Methanol (formic

Respiratory Acidosis and Alkalosis ... Diagnostic Algorithm Anion ... late) Normal anion ... Diagnosis #Acidosis #Alkalosis ... Recommended Text: Nephrology

Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation:
1. Acidemia or Alkalemia?
2.

Anion gap? ... ↑ ↑ Metabolic alkalosis ... Acidosis ↑ ↓ Resp Alkalosis ... of Respiratory alkalosis ... Diagnosis #Summary #Nephrology

Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
• Vomiting
• NG suction
GI

Causes of Metabolic Alkalosis ... suction GI Losses - Lower ... Non-reabsorbed anions ... MetabolicAlkalosis #NonGap #Nephrology

Gowers' Sign on Physical Exam

Seen in this patient with Duchenne muscular dystrophy (DMD)

#Gowers #Sign #PhysicalExam #neurology

Gowers' Sign on ... dystrophy (DMD) #Gowers ... #Sign #PhysicalExam ... #neurology #clinical

Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
• Kidney loss of Cl-

Metabolic Alkalosis ... responsive metabolic alkalosis ... tubular acidosis Anion ... indicated causes of anion ... urine #Algorithm #nephrology

Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?

acidosis or an alkalosis ... respiratory acidosis if lower ... concomitant respiratory alkalosis ... do more work = ANION ... Metabolic #Acidosis #Alkalosis

Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-

to be higher in Asians ... Hypokalemia Metabolic alkalosis ... Pathophysiology #nephrology

Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked

- Metabolic Alkalosis ... Non-reabsorbable anions ... differential #potassium #nephrology

Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal

Beevor's Sign on ... Exam Beevor's sign ... usually reflects lower ... #Beevors #Sign # ... video #umbilicus #neurology

Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or

hypertension and signs ... heart failure, neurologic ... and metabolic alkalosis ... renal bruit or signs ... Neurologic disorders

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