13 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... to be higher in Asians ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... - Metabolic Alkalosis ... Non-reabsorbable anions ... #diagnosis #Algorithm
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Serotonin #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) hypokalemic ... hypomagnesemia • Metabolic alkalosis ... Hypochloremic metabolic alkalosis ... #diagnosis #nephrology ... #management #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... hypertension and signs ... and metabolic alkalosis ... renal bruit or signs ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... hydration - Hyperkalemia ... #TLS #diagnosis
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... lead to metabolic alkalosis ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... Cataracts Labs: Hypokalemia ... hypernatremia, metabolic alkalosis ... #signs #symptoms
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
-> respiratory alkalosis ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... #signs #psychiatry