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diagnosis hematology joint ana antibodies antinuclear bone causes classification comparison dermatology disease erythematosus monoclonal myopathies myopathy myositis oncology paraproteinemias patterns
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... , Gemcitabine Lupus ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody ... lesions • Discoid lupus ... dermatology #joint #pain ... #skin #rashes #differential ... #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Can present from infancy ... predispose to other orthopedic ... • Differentiate ... #diagnosis #causes ... #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antibodies (ANA) ANA or Anti-NucIear ... Antibody refers ... assay (IFA) is the main ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
glomerulonephritis) • Anti-GBM ... Urticarial Vasculitis (anti-C1q ... such as systemic lupus ... , infarct • Small ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
nemaline myopathy • Anti ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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