2812 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... Pleuritis) H Hematologic ... Arthritis R Renal Disease ... erythematosus #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Low Serum B12 - Anti-IF ... Low Serum B12 - Anti-IF ... • Pancreatic Disease ... • Liver Disease ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
PT, aPTT(liver disease ... bypass), LFT (liver disease ... ), HBsAg/anti-HBc ... or if a primary hematologic ... Causes #Workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, anti-Smith ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... , Ro/La, anti-Jo ... Erythematosus #Diagnosis #Rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... Obstructive Pulmonary Disease ... Hypnotics • Anti-hypertensives ... • Anti-Depressants
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Antibodies: Anti-Ro ... /SSA & Anti-La/SSB ... Antibodies: • Anti-Ro ... in primary) • Anti-La ... Nephrogenic DI Hematologic
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... Cold Agglutinin Disease ... Coombs testing for anti-C3d ... and negative anti-lgG ... hemolytic #anemia #hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation

C	Congestive Heart Failure	1

H	Hypertension	1

A2	Age >75	2

D	Diabetes Mellitus	1

S2	Stroke,
2 V Vascular disease ... 1 D Drugs Anti-platelet ... AFib #Diagnosis #Hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... nemaline myopathy • Anti ... anticoagulant • IgM anti-cardiolipin ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... and/or decreased anti-coagulation ... • Hematologic ... Disease: (i.e.