1345 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis, causes ... and management ... - Specific anti-infectious ... the absence of anti-infectious ... with refractory disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... Discontinuation of causal ... Usual therapeutic management ... Evolution: Chronic disease ... rheumatology #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Drugs, Unknown cause ... chemotherapy, anti-CD20 ... Lymphohistiocytosis #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Antibodies: Anti-Ro ... /SSA & Anti-La/SSB ... Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Rheumatology #Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... Inflammatory eye disease ... Goodpasture's cause ... differential #diagnosis #management
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
an autoimmune disease ... - but 5% have anti—muscle-specific ... More likely to cause ... glucocorticoids - can cause ... Gravis #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... or anti-HNA Ab) ... more likely to cause ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... or anti-HNA Ab) ... more likely to cause ... Transfusions #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
levels • NMO-IgG (anti-AQP4 ... • Infectious causes ... MCTD - Bechet disease ... AntiCRMP IgG, Anti-Hu ... Myelitis #diagnosis #management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Anti-NXP-2 Dermatomyositis ... Muscle atrophy may cause ... had more severe disease ... Association of Anti-NXP2 ... Dermatomyositis #diagnosis #management