3550 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
The exact cause ... the formation of anti-PF4 ... antibodies which cause ... that generate anti-PF4 ... thrombocytopenia #COVID #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... Etiological+++: Anti-infectious ... chemotherapy, anti-CD20 ... manifestations, Anti-IFN-y
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
and/or decreased anti-coagulation ... retinal edema caused ... Occlusion #CRAO #pathophysiology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... monophasic Pathophysiology ... levels • NMO-IgG (anti-AQP4 ... • Infectious causes ... AntiCRMP IgG, Anti-Hu
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Jaundice #Pathophysiology ... #Unconjugated #Causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% ... of cases) 2 ... Anti-Sm (Smith) ... Anti-histone (in ... seen in 30—70% of cases
Causes and Pathophysiology of Hypertension

#Causes #Pathophysiology #Hypertension #Primary #Essential #Secondary #Differential

** GrepMed Recommended Text: Guyton and
Causes and Pathophysiology ... Hypertension #Causes ... #Pathophysiology
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Heart Failure - Causes ... , Pathophysiology ... • Other HFpEF Causes ... #HeartFailure #Causes ... #Pathophysiology
Autoimmune Gastritis - Pathophysiology

Anti-ParietaI Cell, CD4+ T Cells, Autoantibodies -> x Parietal Cells, x HCL, x
Autoimmune Gastritis - Pathophysiology ... Anti-ParietaI ... Autoimmune #Gastritis #Pathophysiology