615 results
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... patients on chronic anticoagulation ... and procedural bleeding ... with a very low bleeding ... may not require anticoagulation
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... interactions and bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
therapy = increased bleeding ... - Bleeding ... Unclear if reduced bleeding ... due to use of DOAC ... Triple #therapy #anticoagulation
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... Comparison Table #DOAC ... Anticoagulants #Anticoagulation
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs ... #anticoagulation
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
anticoagulant agents (DOACS ... #DOAC #Dosing #Oral ... #Anticoagulation
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... Clearance #oral #anticoagulation
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... from warfarin to DOACs ... from warfarin to DOACs ... Transitioning #Anticoagulation
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduced DOAC Dosing ... Fibrillation #DOAC ... Reduction #Dose #Anticoagulation