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diagnosis differential management neurology infections infectiousdiseases pharmacology aids anemia antibiotic antimicrobials aplastic bee coverage csf dfis diabetes diabeticfootinfections encephalitis failure
For my UME micro course, I made a figure that captures this terminology and lets learners
of clinically important ... bacteria. ... important drug classes ... Varun Phadke @VarunPhadke2 ... #coverage #antibiogram
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Bug: Atypical bacteria ... Spectrum (MRSA/ ... Tissue penetration (CNS ... • Secondary to Treatment
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Common clinical ... stain: Previous antibiotics ... Develops in the immune ... Singh @rav7ks #CNS
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... present in 15% of cases ... Antimicrobial treatment ... required until immune ... Demyelinating disease caused
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Infections+++: Virus ... CMV, HHV8,...), Bacteria ... Drugs, Unknown cause ... Treatment: •
Diabetic foot infections (DFIs) is a common complication of longstanding diabetes, and it is associated with
neuropathy, peripheral arterial ... (PAD), and the immune ... treatment, and ... require broader spectrum ... the underlying cause
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... Immune-mediated ... nervous system (CNS ... diagnosis and treatment ... MRI lesions and clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... and petechiae Causes ... - β-lactam antibiotics ... aplastic anemia Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... drug-resistant infection, bacterial ... noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS
CSF Penetration of Antimicrobials Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
compared to other antibiotic ... classes. 1 only ... successfully in clinical ... line agents in bacterial ... infections 5 however clinical
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