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management differential hematology algorithm infectiousdiseases oncology product reactions syndrome acquired agep anemia antibiotic aplastic bacteremia causes classification cocci coccidioides coccidioidomycosis
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Anticonvulsants • Antibiotics ... • Epstein-Barr Virus ... Gram Positive Bacteria ... Gram Negative Bacteria ... Algorithm #Causes #Hematology
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Pseudo-cellulitis / "CAP ... Bug: Atypical bacteria ... Aggressive: MRSA bacteremia ... Tissue penetration (CNS ... , Blood stream,
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
pathogen (e.g., bacteria ... Exogenous Pyrogen: • Bacteria ... transport across blood-brain ... circumventricular organs CNS ... InfectiousDiseases #Diagnosis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
Encephalitis and Bacterial ... paresis) features Bacterial ... stain: Previous antibiotics ... differentiate bacterial ... meningitis • In Bacterial
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hematologic: Acute blood ... Rebound effect from treatment ... infections, TB, Acute bacterial ... #Algorithm #hematology
Coccidiomycosis - Diagnosis Diagnosis: • Mildly elevated peripheral WBC, Eosinophilia (25%), Elevated ESR, Procalcitonin normal (95%) •
lobes (unlike bacterial ... trend response to treatment ... skin & joints - Can ... Beta D Glucan in blood ... Puncture only if CNS
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
acid by colonic bacteria ... Polyethylene glycol can ... non-absorbable antibiotic ... ammonia-producing colonic bacteria ... #hepatology
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
Spontaneous Bacterial ... RBCs) • Obtain bacterial ... ascitic fluid in blood ... -40% will have bacterial ... #Spontaneous #Bacterial
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
) - Diagnosis and ... chest pain (LR + NS ... or CT Scan Bacterial ... 96.1% • Empiric antibiotic ... #treatment #Pulmonary
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- β-lactam antibiotics ... aplastic anemia Treatment ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
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