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diagnosis management differential neurology syndrome hematology hemophagocytic hlh infections lymphohistiocytosis rheumatology aids anemia aplastic bee behcet encephalitis hepatorenal hiv hrs
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... • Common clinical ... stain: Previous antibiotics ... Develops in the immune ... Singh @rav7ks #CNS
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... CMV, HHV8,...), Bacteria
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
should be based on clinical ... Antimicrobial treatment ... required until immune ... Demyelinating disease ... • JC-virus PCR
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... : Arterial (MCC-small ... Behcet syndrome (Clinical ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes Immune-mediated ... nervous system (CNS ... and less common diseases ... diagnosis and treatment ... MRI lesions and clinical
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... - β-lactam antibiotics ... HCV - HIV • Immune ... aplastic anemia Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... drug-resistant infection, bacterial ... noncompliance • Clinical ... initiation Clinical ... pleural effusions, CNS
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... underlying genetic immune ... age, however the disease ... rapidly, and empiric antibiotic ... #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... • Immune Mediated ... Transverse Myelitis - Clinical ... Transverse Myelitis Treatment
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... Diagnosis (Clinical ... Treatment Overview ... e.g., alcohol, virus ... Hepatorenal #Syndrome #Hepatology
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