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differential management erythematosus lupus systemic acidosis ana antinuclear antinxp2 antinxp2dm arthritis causes contusion criteria cryoglobulinemia cryoglobulins ctchest dermatology dermatomyositis disease
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... Highly specific antibodies ... #Criteria #SLE ... Erythematosus #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... healthy adults, and should ... likely it will be clinically ... ANA #patterns #rheumatology ... #diagnosis #differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... double-stranded DNA antibodies ... ANAs RF test should ... ANA and RF (if clinical ... #testing #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... Syndrome: • Clinical ... Antineutrophil cytoplasmic antibody ... #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Differential Diagnosis ... Non-autoimmune rheumatologic ... #Rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Presentation: Injury ... Evaluate for NMO, SLE ... Disorders: - SLE ... Antiamphiphysin antibodies
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... again we might see ... liver or renal injury ... gluconeogenesis Liver Injury ... #typea #typeb #classification
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... , and back and shoulders ... auricular papules Clinical ... levels • NXP-2 antibody ... #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... cases such as: • SLE ... : • Clinical tests ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
This patient’s clinical ... Several of the diagnoses ... exam findings and clinical ... Due to their short ... secretions and should
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