67 results
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Pathogenesis and clinical ... a maladaptive antibody-mediated ... produce autoimmune antibodies ... entire complex -> Antibody ... Allergy #Immunology #pathophysiology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
of at least: • 1 ... clinical event ( ... thrombosis) • 1 ... clinical event and ... APS #diagnosis #management
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Pathogenesis and clinical ... Production of lgE Antibodies ... that secrete lgE-antibodies ... -> Allergen-antibody ... Allergy #Immunology #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... this disease is 1/ ... decline in maternal antibody ... or undetectable antibodies ... Agammaglobulinemia #XLinked #pathophysiology
BiPAP titration in CHF
 - Mean airway pressure provides goodness 
 - Ramp up the ePAP
from 5 cm up to 1 ... Driving pressure supports ... CongestiveHeartFailure #Management ... #CriticalCare #
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Detects both HIV antibody ... after exposure • Antibodies ... Phase: • The short ... or HIV-2 antibodies ... antibody test)
Pulmonary Embolism - Risk Stratification and Prognostication based on scores and clinical features

 • Bova score
Prognostication based on scores ... and clinical features ... prognostication #diagnosis #management ... stratification #criticalcare
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1- ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... equina • GQ1b IgG Antibody ... Syndrome #diagnosis #management
COVID-19 Hypoxia Management

Indication for endotracheal intubation?
Tolerating supplemental oxygen?
Consider HFNC
Not tolerating HFNC or HFNC is not available?
Consider
COVID-19 Hypoxia Management ... Monitor closely short ... Society of Critical ... support #COVID19 #management ... #schema #criticalcare
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... - Postulate 1 ... Viral antigen-antibody ... PolyarteritisNodosa #Pathophysiology